翻訳と辞書
Words near each other
・ Mir-552 microRNA precursor family
・ Mir-558 microRNA precursor family
・ Mir-562 microRNA precursor family
・ Mir-569 microRNA precursor family
・ Mir-572 microRNA precursor family
・ Mir-575 microRNA precursor family
・ Mir-58 microRNA precursor family
・ Mir-580 microRNA precursor family
・ Mir-584 microRNA precursor family
・ Mir-589 microRNA precursor family
・ Mir-590 microRNA precursor family
・ Mir-592 microRNA precursor family
・ Mir-598 microRNA precursor family
・ Mir-6 microRNA precursor
・ Mir-601 microRNA precursor family
Mir-605 microRNA precursor family
・ Mir-61 microRNA precursor family
・ Mir-612 microRNA precursor family
・ Mir-615 microRNA precursor family
・ Mir-616 microRNA precursor family
・ Mir-618 microRNA precursor family
・ Mir-62 microRNA precursor family
・ Mir-624 microRNA precursor family
・ Mir-625 microRNA precursor family
・ Mir-632 microRNA precursor family
・ Mir-633 microRNA precursor family
・ Mir-636 microRNA precursor family
・ Mir-638 microRNA precursor family
・ Mir-650 microRNA precursor family
・ Mir-652 microRNA precursor family


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Mir-605 microRNA precursor family : ウィキペディア英語版
Mir-605 microRNA precursor family

In molecular biology mir-605 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.
==p53 protein network==
miR-605 is transcriptionally activated by the p53 protein through interaction with the promoter region of its gene. This microRNA in turn post-transcriptionally represses the oncoprotein and p53 suppressor Mdm2, which acts with p53 in a negative feedback loop in p53-wildtype cancers. Introduction of miR-605 interrupts this p53:Mdm2 interaction and instead there is a positive feedback loop in place, enabling rapid p53 accumulation in response to stress. Such p53 accumulation induces cell cycle arrest and apoptosis.〔 〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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